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건강한 아침

"Imagination is more important than knowledge"

-Albert Einstein-

Food Immunology Laboratory

경희대학교

식품면역연구실

Department of Food Science & Biotechnology

College of Life Science

Kyung Hee University

​경희대학교 생명과학대학 식품생명공학과

Rm B101, Management & International Relations Bldg.

1732, Deogyeong-daero,

Giheung-gu, Yongin-si,

Gyeonggi-do 17104, Korea

경기도 용인시 기흥구 덕영대로 1732

국제경영대학관 지하101호

PI

Principal Investigator

지도교수

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Wooki Kim, Ph.D.

(김우기,kimw at khu.ac.kr)

Associate Professor

Department of Food Science & Biotechnology

College of Life Sciences

Kyung Hee University

[Edudation & Research Training]

B.S. in Biotechnology, Yonsei University (2002)

Researcher, R&D Center, Nongshim Co. (2002-2004)

Ph.D. in Nutirtion Immunology, Texas A&M University (2004-2008), Co-advised by Dr. Robert Chapkin & Dr. David McMurray

Postdoctoral Researcher, Texas A&M University (2009), Advised by Dr. Robert S. Chapkin

Postdoctoral Researcher, Emory University (2010-2012), Co-advised by Dr. Charles Parkos & Dr. Timothy Denning 

[Honors​ & Awards]

Graduate Study Abroad Scholarship, Korea Science and Engineering Foundation (2004)

Regent’s Fellowship, Texas A&M University (2004)

Texas Public Education Grant- International (2006)

P&G Graduate Student Research Award, American Society for Nutrition (2008)

Young Scientist Award (Postdoc), American Society for Investigative Pathology (2011)

Academic Advance Award, Korean Society of Food Science and Technology (2017)

[Professional Memberships]

Managing Committee & Academic Committee, ICOFF 2015 (2013-2015)

Member, Korean Society of Food Science and Technology (2012-present) 

Menber, Korean Society for Food Enginering (2013-present)

Editor, Food Science & Biotechnology(2013-2018)

Managing Editor, Food Engineering Progress (2015-2019)

Editor, Microbiology and Biotechnology Letters (2016-present)

Managing Editor, Food Science & Biotechnology (2019-2020)

Senior Editor, Food Science & Biotechnology (2021-present)

Treasurer, Korean Society of Food Science and Technology (2021)

Members

[Ph.D. Candidates]

[M.S. Candidates]

Members

연구원

Seung Min Yu (유승민, dbtmdals1004 at hanmail.net)

B.S. in Food Science & Biotechnology, Kyung Hee Unviersity

M.S. in Food Science & Biotechnology, Kyung Hee University

Research Topics: Anti-inflammatory mechanisms of sugar replacers with focus on mitochondrial regulation

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Hye Jung Park (박혜정, 9601ys at naver.com)

B.S. in Food Science & Biotechnology, Kyung Hee Unviersity

M.S. in Food Science & Biotechnology, Kyung Hee University

Research Topics: Modulation of glucose uptake in skeletal muscle cells by flavonoids extracted from black rice and black beans

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Sung Min Han (한성민, flyhoper22 at naver.com)

B.S. in Food Science & Biotechnology, Kyung Hee Unviersity

Research Topics: Effects of chain length and unsaturation of fatty acids on macrophage mitochondrial functions

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Seoyoung Kim (김서영, tara4276 at naver.com)

B.S. in Food Science & Biotechnology, Kyung Hee Unviersity

Research Topics: TBD

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[Alumni]

Bitsaem Kim (김빛샘)

Jushin Kim (김주신, 식품의약품안전처)

Bomi Kim (김보미, 이롬라이프)

Minkyung Kim (김민경)

Guihwan Na (나귀환, 코스맥스바이오)

Yeji Kwon (권예지)

Sojung Lee (이소정, 한국콜마)

Insu Ban (반인수, 코스맥스바이오)

Suyeon Choi (최수연)

Hyunseong Kim (김현성, 서흥)

Yonghyun Cho (조용현, 아이엠바이오로직스)

Research

Research

​연구주제

  • Dietary regulation of immune systems

  • Regulation of inflammation by dietary lipids through M1/M2 dichotomy

  • Defining molecular mechanisms of fatty acids on regulation of cellular energy metabolism

  • Anti-inflamamtory mechanisms of sugar replacers​

  • Development of food ingredients for prevention of muscle loss in enderly

  • Futre of foods: Pioneering for platforms of personalized edible oils​

Publications

Publications

​발표논문​

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[2021]

Choi S, Yu S, Lee J, Kim W. Effects of neohesperidin dihydrochalcone (NHDC) on oxidative phosphorylation, cytokine production, and lipid deposition. Foods 10, 1408 (2021)

Park H*, Yu S*, Kim W. Rice bran oil attenuates chronic inflammation by inducing M2 macrophage switching in high-fat diet-fed obese mice. Foods 10, 359 (2021)

*equally contributed

[2020]

 

Kim H, Ban I, Choi Y, Yu S, Youn SJ, Baik MY, Lee H*, Kim W*. Puffing of turmeric (Curcuma longa L.) enhances its anti-inflammatory effects by upregulating macrophage oxidative phosphorylation. Antioxidants 9, 931 (2020)

*co-correspondence

 

Kim H, Choi Y, Yu S, Go GW, Baik M, Kim W. Anti-inflammatory effects of puffed turmeric extract with oriental herb extract in acute colitis mice. Korean Journal of Food Science and Technology 52, 482-486 (2020)

 

Choi Y*, Kim W*; Lee JS, Youn SJ, Lee H, Baik MY. Enhanced Antioxidant Capacity of Puffed Turmeric (Curcuma longa L.) by High Hydrostatic Pressure Extraction (HHPE) of Bioactive Compounds. Foods  9, 1690 (2020)

*equally contributed

 

Kim J, Lee, HI, Lim YJ, Park YJ, Kim W, Kim DO, Kim BY, Eom SH, Baik MY. Antioxidant and phytoestrogenic activities of puffed black soybeans (Glycine max). LWT 118, 108780 (2020)

 

Kang EY, Kim HK, Moyo KM, Gang G, Kim W, Go GW. Corn silk extracts did not alter the adiposity and underlying substrate utilization in high-fat diet-induced obese C57BL/6 mice. Korean Journal of Food Science and Technology 52, 144-148 (2020)

 

Kim HK, Jung J, Kang EY, Gang G, Kim W, Go GW. Aronia melanocarpa reduced adiposity via enhanced lipolysis in high-fat diet-induced obese mice. Korean Journal of Food Science and Technology 52, 255-262 (2020)

 

[2019]

Shin JH, Park YJ, Kim W,Kim DO, Kim BY, Lee H, Baik MY. Change of Ginsenoside Profiles in Processed Ginseng by Drying, Steaming, and Puffing. Journal of Microbiology and Biotechnology 29, 222-229 (2019)

 

Kwon Y, Yu S, Choi GS, Kim JH, Baik M, Su ST, Kim W. Puffing of Rehmannia glutinosa enhances anti-oxidant capacity and down-regulates IL-6 production in RAW 264.7 cells. Food Science and Biotechnology 28, 1235-1240 (2019)

 

Luissint AC, Williams HC, Kim W, Flemming S, Azcutia V, Hilgarth RS, O’Leary MN, Denning TL, Nusrat A, Parkos CA. Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice. Mucosal Immunology 12, 668-678 (2019)

 

Kim HK, Choi JH, Kim HJ, Kim W, Go GW. Medium-chain fatty acid enriched-diacylglycerol (MCE-DAG) accelerated cholesterol uptake and synthesis without impact on intracellular cholesterol level in HepG2. Korean Journal of Food Science and Technology 51, 272-277 (2019)

 

Lee S, Yu S, Park HJ, Jung J, Go, GW*, Kim W*. Rice bran oil ameliorates inflammatory responses by enhancing mitochondrial respiration in murine macrophages. PloS one 14, e0222857 (2019)

*co-correspondence

 

Choi, Y, Ban I, Lee H, Baik MY*, Kim W*. Puffing as a Novel Process to Enhance the Antioxidant and Anti-Inflammatory Properties of Curcuma longa L.(Turmeric). Antioxidants 8, 506 (2019)

*co-correspondence

 

Yu S, Go GW*, Kim W*. Medium Chain Triglyceride (MCT) Oil Affects the Immunophenotype via Reprogramming of Mitochondrial Respiration in Murine Macrophages. Foods 8, 553 (2019)

*co-correspondence

 

Kim MS, Jeon SJ, Youn SJ, Lee H, Park YJ, Kim DO, Kim BY, Kim W, Baik MY. Enhancement of minor ginsenosides contents and antioxidant capacity of american and canadian ginsengs (Panax quinquefolius) by puffing. Antioxidants 8, 527 (2019)

[2018]

 

Kim W, Kim SY, Kim DO, Kim BY, Baik MY. Puffing, a novel coffee bean processing technique for the enhancement of extract yield and antioxidant capacity. Food Chemistry 240, 594-600 (2018)

 

Han GE, Kang HT, Chung S, Lin C, Linton JA, Lee JH, Kim W, Kim SH, Lee JH. Novel neohesperidin dihydrochalcone analogue inhibits adipogenic differentiation of human adipose-derived stem cells through the Nrf2 pathway. International Journal of Molecular Sciences 19, 2215 (2018)

 

[2017]

 

Jeng HY, Choi YS, Lee JK, Lee BJ, Kim W, Kang H. Anti-inflammatory activity of citric acid-treated wheat germ extract in lipopolysaccharide-stimulated macrophages. Nutrients 9, 730 (2017)

 

Yu S, Choi JH, Kim HJ, Park SH, Go, GW*, Kim W*. In Vitro Evidence of Anti-Inflammatory and Anti-Obesity Effects of Medium-Chain Fatty Acid-Diacylglycerols. Journal of Microbiology and Biotechnology, 27, 1617-1627 (2017)

*co-correspondence

 

Kim H, Choe JH, Choi JH, Kim HJ, Park SH, Lee MW, Kim W, Go GW. Medium-chain enriched diacylglycerol (MCE-DAG) oil decreases body fat mass in mice by increasing lipolysis and thermogenesis in adipose tissue. Lipids 52, 665-673 (2017)

 

Ahn H, Jeong J, Moyo KM, Ryu Y, Min B, Yun SH, Kim HY, Kim W, Go GW. Downregulation of Hepatic De Novo Lipogenesis and Adipogenesis in Adipocytes by Pinus densiflora Bark Extract. Journal of Microbiology and Biotechnology 27, 1925-1931 (2017)

 

Lee G, Choi GS, Lee JY, Yun SJ, Kim W, Lee H, Baik MY, Hwang JK. Proximate Analysis and Antioxidant Activity of Cultivated Wild Panax ginseng. Food Engineering Progress 21, 208-214 (2017)

 

Lee G, Na G, Kim W, Baik M, Lee H, Hwang JK. Anti-inflammatory Effect of Cultivated Wild Panax ginseng Extracts at Various Ages in RAW264. 6 Macrophages. Food Engineering Progress 21, 201-207 (2017)

 

[2016]

 

Kim B, Lee JH, Seo MJ, Eom SH, Kim W. Linarin down-regulates phagocytosis, pro-inflammatory cytokine production, and activation marker expression in RAW264. 7 macrophages. Food Science and Biotechnology 25, 1437-1442 (2016)

 

[2015]

 

Han S, Choi SH, Kim W, Kim BY, Baik MY. Infusion of catechin into native corn starch granules for drug and nutrient delivery systems. Food Science and Biotechnology 24, 2035-2040 (2015)

 

Kim SK, Choi SH, Choi HW, Ko JH, Kim W, Kim DO, Kim BY, Baik MY. Retrogradation kinetics of cross-linked and acetylated corn starches under high hydrostatic pressure. Food Science and Biotechnology 24, 85-90 (2015)

 

Jin JH, Chun EH, Hyun JH, Choi SW, Su ST, Kim W, Kim DO, Kim BY, Baik MY. Optimization of hot water extraction and ultra high pressure extraction for deer antler. Food Science and Biotechnology 24, 507-512 (2015)

 

Kim AY, Kim W,Kim DO, Kim HY, Kim BY, Baik MY, Lee H. Effects of moisture content and puffing pressure on extraction yield and antioxidant activity of puffed 21-year-old Platycodon grandiflorum roots. Food Science and Biotechnology 24, 1293-1299 (2015)

 

[2014]

 

Kim W, Barhoumi R, Mcmrray DN, Chapkin RS. Dietary fish oil and DHA down-regulate antigen-activated CD4+ T-cells while promoting the formation of liquid-ordered mesodomains. British Journal of Nutrition 111, 254-260 (2014)

 

Chang YJ, Choi HW, Kim HS, Lee HJ, Kim W,Kim DO, Kim BY, Baik MY. Physicochemical properties of granular and non-granular cationic starches prepared under ultra high pressure. Carbohydrate Polymers 99, 385-393 (2014)

 

Yoo HG, Lee BH, Kim W,Lee JS, Kim GH, Chun OK, Goo SI, Kim DO. Lithospermum erythrorhizon extract protects keratinocytes and fibroblasts against oxidative stress. Journal of Medicinal Food 17, 1189-1196 (2014)

 

Lee AR, Choi SH, Chioi HW, Ko JH,Kim W, Kim DW, Kim BY, Baik MY. Optimization of ultra high pressure extraction (UHPE) condition for puffed ginseng using response surface methodology. Food Science and Biotechnology 23, 1151-1157 (2014)

 

[2013]

 

Choi MS, Kim W, Lee C, Oh CS. Harpins, multifunctional proteins secreted by gram-negative plant-pathogenic bacteria. Molecular Plant-Microbe Interactions 26, 1115-1122 (2013)

 

Seo DW, Cho YR, Kim W,Eom SH. Phytochemical linarin enriched in the flower of Chrysanthemum indicum inhibits proliferation of A549 human alveolar basal epithelial cells through suppression of the Akt-dependent signaling pathway. Journal of Medicinal Food 16, 1086-1094 (2013)

 

Kim W, Lee H. Advances in nutritional research on regulatory T-cells. Nutrients 5, 4305-4315 (2013)

 

Cho A, Choi SH, Choi HW, Kim HS, Kim W, Kim DO, Kim BY, Baik MY. Characterization of cationic dextrin prepared by ultra high pressure (UHP)-assisted cationization reaction. Carbohydrate polymers 97, 130-137 (2013)

 

Khounlotham M, Kim W, Peatman E, Nava P, Medina-Contreras O, Addis C, Koch S, Fournier B, Nusrat A, Denning TL. Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis. Immunity 37, 563-573 (2012)

 

[2012]

 

Jung JH, Lee JH, Holden JF, Seo DH, Shin H, Kim HY, Kim W, Ryu S, Park CS. Complete genome sequence of the hyperthermophilic archaeon Pyrococcus sp. strain ST04, isolated from a deep-sea hydrothermal sulfide chimney on the Juan de Fuca Ridge. Journal of Bacteriology 194, 4434-4435          (2012)

 

Monk J, Kim W,Callaway E, Turk HF, Foreman JE, Peters JM, He W, Weeks B, Alaniz RC, Robert C, McMurray DN. Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis. American Journal of Physiology-Gastrointestinal and Liver Physiology 302, G153-G167 (2012)

 

Geen D, Medina-Conteras O, Kim W, Huang C, Denning TL. Isolation and characterization of dendritic cells and macrophages from the mouse intestine. JoVE e4040 (2012)

 

Seo DH, Jung JH, Lee JE, Jeon EJ, Kim W, Park CS. Biotechnological production of arbutins (α-and β-arbutins), skin-lightening agents, and their derivatives. Applied Microbiology and Biotechnology  95, 1417-1425 (2012)

 

Lim D, Kim W, Lee MG, Heo HJ, Chun OK, Kim DO. Evidence for protective effects of coffees on oxidative stressinduced apoptosis through antioxidant capacity of phenolics. Food Science and Biotechnology 21, 1735-1744 (2012)

Photos

Gallery

​사진​

Contact

Contacts

연락처

Food Immunology Lab is a group of young, active, and innovative scientists. Any self-motivated candidate with scientific curiosity on nutritional modulation of immune responses should send an e-mail to [kimw at khu.ac.kr] or call [+82-31-201-3482].

저희 실험실은 젊고 역동적이면서도 창의적인 연구를 지향하며, 

​식품면역학 분야의 자기주도적 미래인재를 언제나 기다립니다.

kimw at khu.ac.kr로 이메일 또는 031-201-3482로 전화 주세요.

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